Immunotherapy (CIC – Combined Immunotherapy for Cancer) is one of the key advanced treatment strategies at Fuda Cancer Hospital, Guangzhou. It enhances the body's immune defense system to fight cancer cells while also complementing other treatments like cryosurgery, radiofrequency ablation, and chemotherapy.

The active practice of immunotherapy has rapidly advanced due to breakthroughs in immune checkpoint inhibitors and chimeric antigen receptor T-cell (CAR-T) therapy. Studies have shown improved survival when immunotherapy is combined with minimally invasive interventions or traditional cancer treatments.

Comprehensive Targeted Therapy & Immunotherapy Strategy

Systemic and Localized Combination: Localized methods such as cryo-ablation, radiofrequency ablation, radiation, and surgery reduce tumor burden, setting the stage for systemic immunotherapy to act effectively. Freezing therapy produces a “cold immune” effect, which combined with immunotherapy, strengthens the body’s natural anti-tumor response.

Multiple Mechanisms Synergy: Using different immunotherapeutic methods—like CIK, DC, and TCM therapies—enhances various immune pathways. Sequential or combined approaches can comprehensively improve immune system performance against cancer.

Guidelines for Immunotherapy Application

• Following surgical removal of solid tumors.
• For metastatic tumors unsuitable for surgery (palliative treatment).
• For recurrent or relapsing cancers.
• For benign tumors that require intervention but cannot be surgically removed.

At Fuda Cancer Hospital – Guangzhou, immunotherapy is an integral part of a holistic cancer care model that goes beyond chemotherapy and radiation. Alongside cryosurgery, Fuda’s immunotherapy programs help rebuild the immune system, prevent metastasis, and improve patients’ overall well-being.

Types of Immunotherapy at Fuda Cancer Hospital

• CIK (Cytokine-Induced Killer Cells): Boosts the immune system’s ability to destroy tumor cells.
• DC (Dendritic Cell Therapy): Helps the immune system recognize and attack cancer cells.
• TCM (Traditional Chinese Medicine): Strengthens the immune system and supports recovery post-treatment.

These immunotherapies have proven highly effective in slowing cancer growth, preventing metastasis, and reducing recurrence rates. They are particularly beneficial for patients whose immune systems have been weakened by chemotherapy or radiation.

Background

Over the last decade, immunotherapy has become a cornerstone in modern oncology. The development of immune checkpoint inhibitors and the understanding of tumor immune evasion mechanisms have opened new doors for cancer treatment. Fuda Cancer Hospital pioneered combining CIC (Combined Immunotherapy for Cancer) with cryosurgery, achieving significant clinical success recognized by international cancer research societies.

Since 1991, thousands of patients with advanced or relapsed cancers have benefited from Fuda’s CIC program. Results show extended survival, improved quality of life, and reduced cancer recurrence and metastasis rates.

Concept

Cancer often develops in bodies with compromised defense and repair functions. Enhancing a patient’s immune function can help control or even suppress cancer activity, placing the disease into a manageable, chronic state. CIC aims to treat both the tumor and the underlying conditions that allowed cancer to develop, addressing cancer as a systemic disease rather than a localized one.

As stated by the World Health Organization (WHO), cancer is considered a chronic disease. The CIC model at Fuda Cancer Hospital plays a vital role in turning cancer into a controllable condition, improving long-term survival and life quality.

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